L-methylfolate (Deplin®/Enlyte®) (Medical Food)
FDA Approved for:Suboptimal folate levels in depressed patients (adjunct to antidepressant) & Hyperhomocysteinemia in schizophrenia patients (adjunct to antipsychotic)
Doses: 15 mg to 30 mg per day
Aspect of B vitamin that crosses blood brain-barrier (BBB)
Why not vitamin B6 (Pyridoxine) or B9 (Folic acid)?
L-methylfolate ; Regulator of homocysteine; increases plasma homocysteine; risk factor in development of Alzheimers (ALZ); L-methylfolate decreqwew homocysteine levels especially in patients with decreased plasma folate
Note: ALZ patients may suffer from decreases plasma folate and l-methylfolate levels
Juven® (Medical Food)
Indications: Supports tissue building; Diseases that cause weight loss, cachexia, and age related muscle loss (sarcopenia)
Ingredients: HMB (hydroxymethylbutyrate), L-leuine, L-glutamine
Mechanism of Action: Inhibition of protein breakdown & stimulation of mTOR (mammalian target of rapamycin) pathway
App Trim® (Medical Food)
Indications: Obesity; Insulin resistance & forms of metabolic dysfunction
Ingredients: Whey protein, amino acids, Griffonia seed extract, cocoa, caffeine
Mechanism of Action: Increase amino acids involved in appetite regulation increase lipolysis
Sentra PM® (Medical Food)
Indications: Depression related sleep disorders
Ingredients: NT precursors, polyphenols
Mechanism of Action: Neurotransmitters involved in sleep regulation
GABAdone® (Medical Food)
Indications: Management of metabolic processes associated with sleep disorders
Ingredients: Choline bitartrate, GABA, cocoa extract, l-glutamine, whey protein isolate, Griffonia extract, valerian root, acetyl l-carnitine, ginko biloba, grape seed extract
Mechanism of Action: Supports NT that regulate sleep: serotonin, GABA, Ach – More research needed
Trepadone® (Medical Food)
Indications: Pain, inflammation syndromes, arthritis
Ingredients: Whey protein, GABA, L-histidine, glucosamine/chondroitin, omega-3-fatty acids,
polyphenols
Mechanism of Action: Supports synthesis of NTs involved in managing joint disease
Theramine®(Medical Food)
Indications: Management of metabolic processes associated with pain/inflammatory conditions & chronic pain
Ingredients: GABA, choline, whey protein, arginine, histidine, glutamine, theobromine, Griffonia seed, grape seed, serine, cinnamon
Mechanism of Action: Stimulates GABA, serotonin, & norepinephrine
Pulmona® (Medical Food)
Indications:Management of metabolic processes associated with pulmonary hypertension & bronchospasm
Ingredients: L-arginine, l-glutamine, l-histidine, l-leucine, lcysteine, choline bitartrate, whey protein hydrolysate, cinnamon, ginkgo biloba, grape seed extract, caffeine, cocoa extract
Mechanism of Action: Improves endothelial function, lowers hypertension via production of nitric oxide
Vascazen® (Medical Food)
Indications:Cardiovascular disease; dietary Management of omega-3 deficiency
Ingredients: EPA and DHA in patented 6:1 ratio
Mechanism of Action: Inhibition of pro-inflammatory eicosanoids; Increased production of anti-inflammatory eicosanoids & Down regulation of NFKB, major inflammatory pathway
Limbrel® (Medical Food)
Indications: Osteoarthritis
Ingredients: Polyphenol flavonoids
Mechanism of Action: COX-2 (pro-inflammatory) inhibitors and 5-LOX (lipoxygenase) pathways
Axona® (Medical Food)
Indications: Alzheimer’s Disease
Ingredients: Caprylic Acid, Medium Chain Triglyceride
Mechanism of Action: Inhibition of protein breakdown & stimulation of mTOR (mammalian target of rapamycin) pathway
Cerefolin NAC® (Medical Food)
Indications: Cognitive Impairment
Ingredients: B12, , L-methylfolate, NAC (N-Acetyl cysteine)
Mechanism of Action: Regulator of homocysteine levels & MTHFR (methylene-tetra-hydrofolate reductase, involved in folate production) polymorphism
Vayarin® Lipirinen™ ADHD (Medical Food)
Omega-3-Long Chain Polyunsaturated Fatty Acids
No sugar, lactose, yeast, or gluten
Avoid with Anti- & Cholinergic Meds
Avoid with shellfish allergies
Composed of 167 mg of Lipirinen™:Phosphatidylserine (PS); Eicosapentaenoic Acid (EPA) & Docosahexaenoic Acid (DHA)
National Nutrient Database
http://ndb.nal.usda.gov/
Comprehensive Data Base (8000 Foods)
Foods sorted by specific nutrients (e.g., omega-3, magnesium, folate)
Includes Restaurant Foods
